Prediction of BMI traits in the Chinese population based on the gut metagenome
Yu Liang, Shujie Dou, Guangzhong Zhao, Jie Shen, Guangping Fu, Lihong Fu, Shujin Li, Bin Cong, Chunnan Dong · 2023
Read Prediction of BMI traits in the Chinese population based on the gut metagenome by Yu Liang, Shujie Dou, Guangzhong Zhao, Jie Shen, Guangping Fu, Lihong Fu, Shujin Li, Bin Cong, Chunnan Dong (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10704812.txt.
Description
Yu Liang and co-authors read body weight from the genes of gut bacteria. Their 2023 forensic-leaning study uses metagenomic data from healthy Chinese volunteers to predict body mass index, testing whether stool traces could one day betray a suspect's build.
Group profiles differed by weight, and a model built on thirty-one bacterial species predicted BMI with moderate accuracy. The gene level did better: variant patterns across the microbes' genomes, distilled to sixty-two key segments, predicted BMI more tightly, and a body-type classifier sorted over ninety-three percent of participants correctly. Underweight and overweight groups each showed distinctive diversity patterns. The authors present gut genetics as a promising forensic marker, stable and personal enough to profile from traces.
Catalog record
| CREATOR | Yu Liang, Shujie Dou, Guangzhong Zhao, Jie Shen, Guangping Fu, Lihong Fu, Shujin Li, Bin Cong, Chunnan Dong |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |