Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy
Mathieu Pavoine, Philippe Thuillier, Nicolas Karakatsanis, Delphine Legoupil, Karim Amrane, Romain Floch, Romain Le Pennec, Pierre-Yves Salaün, Ronan Abgral, David Bourhis · 2023
Read Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy by Mathieu Pavoine, Philippe Thuillier, Nicolas Karakatsanis, Delphine Legoupil, Karim Amrane, Romain Floch, Romain Le Pennec, Pierre-Yves Salaün, Ronan Abgral, David Bourhis (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10703763.txt.
Description
Ten authors led by Mathieu Pavoine swap patient blood read curves for a stock curve to shorten full-body cancer scans. The scans track sugar-tagged tracers in spread skin cancer under immune care. True maths of uptake needs the blood curve for a full hour post-dose. A stock curve, fit once on a group and scaled per patient, cuts that need.
Thirty-seven patients from a live trial fed the build and check sets. Stock and true curves matched well across nine short cut spans of the hour. Uptake rates for organs, growths, and flare spots held near tied by both paths. Short scans mean less bed time and less ill rest for frail patients.
Catalog record
| CREATOR | Mathieu Pavoine, Philippe Thuillier, Nicolas Karakatsanis, Delphine Legoupil, Karim Amrane, Romain Floch, Romain Le Pennec, Pierre-Yves Salaün, Ronan Abgral, David Bourhis |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |