Targeted metabolomics reveals the association between central carbon metabolism and pulmonary nodules
Yue-yang Wu, Wen-bin Shen, Jian-wei Li, Meng-yu Liu, Wen-lei Hu, Sheng Wang, Jian-jun Liu, Fen Huang, Qi-rong Qin, Bashir Sajo Mienda, Bashir Sajo Mienda, Bashir Sajo Mienda · 2023
Read Targeted metabolomics reveals the association between central carbon metabolism and pulmonary nodules by Yue-yang Wu, Wen-bin Shen, Jian-wei Li, Meng-yu Liu, Wen-lei Hu, Sheng Wang, Jian-jun Liu, Fen Huang, Qi-rong Qin, Bashir Sajo Mienda, Bashir Sajo Mienda, Bashir Sajo Mienda (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10703222.txt.
Description
Yue-yang Wu and eight co-authors link blood metabolites to lung nodules in a study from 2023. Lung nodules are small spots found on chest scans, and most are harmless, but some mark early disease. The team measured sixteen metabolites from central carbon metabolism in blood from nearly two thousand adults who had low-dose chest scans in a screening cohort.
Statistical methods that correct for self-selection and tangled measures found four metabolites tied to higher nodule risk and two tied to lower risk. The joint effect of all sixteen together leaned positive but was not firm. The authors call for more work on the biology behind the links.
Catalog record
| CREATOR | Yue-yang Wu, Wen-bin Shen, Jian-wei Li, Meng-yu Liu, Wen-lei Hu, Sheng Wang, Jian-jun Liu, Fen Huang, Qi-rong Qin, Bashir Sajo Mienda, Bashir Sajo Mienda, Bashir Sajo Mienda |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |