Increased circulating FGF21 level predicts the burden of metabolic demands and risk of vascular diseases in adults with type 2 diabetes
Zhen Liu, Yue Peng, Supeng Li, Yusheng Lin, Yunfeng Huang, Wenting Chen, Chunhua Bao, Zengxian Zhou, Zhuofeng Lin, Liangmiao Chen · 2023
Read Increased circulating FGF21 level predicts the burden of metabolic demands and risk of vascular diseases in adults with type 2 diabetes by Zhen Liu, Yue Peng, Supeng Li, Yusheng Lin, Yunfeng Huang, Wenting Chen, Chunhua Bao, Zengxian Zhou, Zhuofeng Lin, Liangmiao Chen (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10702049.txt.
Description
Zhen Liu and co-authors test in this 2023 study whether a liver hormone in the blood flags blood vessel disease in type 2 diabetes. The hormone, FGF21, helps steer sugar and fat handling and rises under metabolic strain. In 701 diabetic patients and 258 healthy controls, the team measured the hormone and checked neck artery disease and high blood pressure.
Levels ran far higher in patients carrying either condition, and highest when both struck together. The hormone tracked body weight and artery wall thickness, and stood as an independent predictor after standard risks were counted. The authors propose it as a gauge of metabolic load and vessel risk. A blood draw could sort risk at checkups.
Catalog record
| CREATOR | Zhen Liu, Yue Peng, Supeng Li, Yusheng Lin, Yunfeng Huang, Wenting Chen, Chunhua Bao, Zengxian Zhou, Zhuofeng Lin, Liangmiao Chen |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |