An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease

Yu Zhang, Ce Zhang, Lin Jiang, Lianjun Xu, Jian Tian, Xueyan Zhao, Dong Wang, Yin Zhang, Kai Sun, Channa Zhang, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Jizheng Wang, Xinxing Feng, Jinqing Yuan, Lei Song · 2023

Read An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease by Yu Zhang, Ce Zhang, Lin Jiang, Lianjun Xu, Jian Tian, Xueyan Zhao, Dong Wang, Yin Zhang, Kai Sun, Channa Zhang, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Jizheng Wang, Xinxing Feng, Jinqing Yuan, Lei Song (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10702040.txt.

Description

When all three main heart arteries are narrowed, doctors must choose between bypass surgery, stents, or medicine alone, and a simple blood measure may help. Yu Zhang and co-authors studied 8,862 such patients and tracked the TyG index, a score built from blood fats and sugar that reflects insulin resistance. Over a median follow up of seven and a half years, patients above the index cutoff had a clearly higher risk of major cardiac events.

The risk signal was strong in patients with diabetes but absent in those without it. Treatment comparisons also shifted with the score: bypass surgery beat stents when the index was normal, yet lost its edge when the index was high. The edge returned only for patients with both a heart attack presentation and diabetes. The authors propose the index as a low cost aid for sorting risk and choosing treatment in this group.

Catalog record

CREATORYu Zhang, Ce Zhang, Lin Jiang, Lianjun Xu, Jian Tian, Xueyan Zhao, Dong Wang, Yin Zhang, Kai Sun, Channa Zhang, Bo Xu, Wei Zhao, Rutai Hui, Runlin Gao, Jizheng Wang, Xinxing Feng, Jinqing Yuan, Lei Song
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10702040

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