Multifunctional gold nanoparticles for osteoporosis: synthesis, mechanism and therapeutic applications

Weihang Gao, Chen Liang, Ke Zhao, Mingming Hou, Yinxian Wen · 2023

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Description

Weihang Gao and four co-authors review gold nanoparticles as a candidate osteoporosis therapy that could build bone and slow its breakdown simultaneously. Current drugs each do one job or the other and carry side effects and costs. Gold particles, biocompatible and optically distinctive, have been shown to push bone-forming cells to mature, restrain the bone-eating cells, and divert fat stem cells away from becoming fat.

The review covers how the particles are synthesized and how size, shape, and surface chemistry steer their effects in cell and animal studies. It weighs drawbacks honestly alongside the promise. Several research directions are flagged as most likely to move the particles toward clinical reality.

Catalog record

CREATORWeihang Gao, Chen Liang, Ke Zhao, Mingming Hou, Yinxian Wen
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10702032

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