Overlapping Stevens-Johnson Syndrome and DRESS Syndrome Caused by Phenobarbital: A Vietnamese Case Report
Khiem Van Nguyen, Quang Van Vu, Mai Hoang Tran, Huy Quoc Nguyen, Chi Quynh Le, Bang Cam Thi Dang, Hieu Chi Chu, Dinh Van Nguyen · 2023
Read Overlapping Stevens-Johnson Syndrome and DRESS Syndrome Caused by Phenobarbital: A Vietnamese Case Report by Khiem Van Nguyen, Quang Van Vu, Mai Hoang Tran, Huy Quoc Nguyen, Chi Quynh Le, Bang Cam Thi Dang, Hieu Chi Chu, Dinh Van Nguyen (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10699157.txt.
Description
Nguyen and co-authors report a rare drug reaction in a young child in a 2023 case paper from Vietnam. Two severe skin reaction syndromes, Stevens Johnson and DRESS, can overlap, and telling them apart in children is hard. Their patient, a boy of 59 months, developed rash, fever, and multi organ trouble after starting phenobarbital for epilepsy.
Skin biopsy and standard criteria backed the overlap diagnosis. Treatment paired immune globulin infusions with corticosteroids and full supportive care, and the child recovered. Overlap cases punish slow recognition, since both syndromes can turn fatal. The report adds a pediatric data point to a literature built mostly on adults.
Catalog record
| CREATOR | Khiem Van Nguyen, Quang Van Vu, Mai Hoang Tran, Huy Quoc Nguyen, Chi Quynh Le, Bang Cam Thi Dang, Hieu Chi Chu, Dinh Van Nguyen |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |