Efficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis
Xiaochen Qiao, Lei Yan, Yi Feng, Xiaoyan Li, Kun Zhang, Zhi Lv, Chaojian Xu, Sen Zhao, Fengrui Liu, Xihua Yang, Zhi Tian · 2023
Read Efficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis by Xiaochen Qiao, Lei Yan, Yi Feng, Xiaoyan Li, Kun Zhang, Zhi Lv, Chaojian Xu, Sen Zhao, Fengrui Liu, Xihua Yang, Zhi Tian (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10687893.txt.
Description
Xiaochen Qiao and ten colleagues rank the injection treatments for knee osteoarthritis in one combined analysis. Steroid shots, hyaluronic acid, and platelet-rich plasma all promise relief, alone or mixed. Head-to-head trials cover only some pairs, so a network method is needed to compare them all.
The review pooled thirty-five trials with over three thousand patients. Platelet-rich plasma gave the best joint function scores at three and twelve months. Its mix with hyaluronic acid led pain scores at several points instead. Steroids trailed at the later checks despite their quick action. Safety events were tracked alongside. The authors back plasma-based shots for lasting benefit.
Catalog record
| CREATOR | Xiaochen Qiao, Lei Yan, Yi Feng, Xiaoyan Li, Kun Zhang, Zhi Lv, Chaojian Xu, Sen Zhao, Fengrui Liu, Xihua Yang, Zhi Tian |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |