Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis
Molly T Radosevich, Scott J Bornheimer, Majid Mehrpouryan, Bita Sahaf, Jean S Oak, Crystal L Mackall, Sabine Heitzeneder · 2023
Read Antigen density quantification of cell-surface immunotherapy targets by flow cytometry: Multi-antigen assay of neuroblastoma bone marrow metastasis by Molly T Radosevich, Scott J Bornheimer, Majid Mehrpouryan, Bita Sahaf, Jean S Oak, Crystal L Mackall, Sabine Heitzeneder (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10684814.txt.
Description
Molly Radosevich and co-authors wrote a 2023 protocol for measuring marker levels on cancer cells in the lab. The cancer is a tumor of nerve tissue that mostly strikes children and can spread to bone marrow. New immune treatments aim at markers on the tumor surface, and their strength depends on how many markers each cell carries.
The protocol counts markers for six targets at once on tumor cells from patient samples. Steps cover taking samples, building the test panel, setting up the machine, and reading the results. Exact counts help doctors judge which patients may gain most from a given treatment.
Catalog record
| CREATOR | Molly T Radosevich, Scott J Bornheimer, Majid Mehrpouryan, Bita Sahaf, Jean S Oak, Crystal L Mackall, Sabine Heitzeneder |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 95 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |