Exploring Environmental Settings to Improve the Printability of Paroxetine-Loaded Filaments by Fused Deposition Modelling
Sara Figueiredo, Ana I Fernandes, Fátima G Carvalho, João F Pinto, Angela Assunta Lopedota, Tatsuaki Tagami · 2023
Read Exploring Environmental Settings to Improve the Printability of Paroxetine-Loaded Filaments by Fused Deposition Modelling by Sara Figueiredo, Ana I Fernandes, Fátima G Carvalho, João F Pinto, Angela Assunta Lopedota, Tatsuaki Tagami (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10675712.txt.
Description
Sara Figueiredo and co-authors study how storage conditions affect drug-loaded filaments for three-dimensional printing of tablets, in a 2023 paper. Filaments are first melted and formed, then fed to a printer at the point of care. Damp air can soften them and spoil feeding.
Filaments carrying an antidepressant were stored at varied humidity and dried by several methods. Under humid storage the filaments stayed bendy and fed poorly. Under dry storage they stiffened and printed well. Passive drying in a sealed dry box was slow, while heat and microwave drying sped the wait. Pre-drying raw mixes did not help. The authors favour microwave drying of finished filaments to allow on-demand printing in clinics.
Catalog record
| CREATOR | Sara Figueiredo, Ana I Fernandes, Fátima G Carvalho, João F Pinto, Angela Assunta Lopedota, Tatsuaki Tagami |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |