Implications of Flagellar Attachment Zone Proteins TcGP72 and TcFLA-1BP in Morphology, Proliferation, and Intracellular Dynamics in Trypanosoma cruzi
Normanda Souza-Melo, Carolina de Lima Alcantara, Juliana Cunha Vidal, Gustavo Miranda Rocha, Wanderley de Souza, Fernando Villalta · 2023
Read Implications of Flagellar Attachment Zone Proteins TcGP72 and TcFLA-1BP in Morphology, Proliferation, and Intracellular Dynamics in Trypanosoma cruzi by Normanda Souza-Melo, Carolina de Lima Alcantara, Juliana Cunha Vidal, Gustavo Miranda Rocha, Wanderley de Souza, Fernando Villalta (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10675206.txt.
Description
Normanda Souza-Melo and co-authors study tail anchor proteins in a parasite in 2023. Trypanosoma cruzi causes Chagas disease and reshapes itself at each life stage. A zone that glues its tail to the body steers growth and inner layout. Two proteins of that zone were little known in this species.
The team used gene editing to tag and delete the proteins in the insect stage of the parasite. They then tracked shape, growth, and inner movement of parts. Lessons from kin species did not fully transfer, which makes the direct test valuable. Knowing the glue zone may expose weak points in a hardy parasite.
Catalog record
| CREATOR | Normanda Souza-Melo, Carolina de Lima Alcantara, Juliana Cunha Vidal, Gustavo Miranda Rocha, Wanderley de Souza, Fernando Villalta |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |