Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted Strategies

Amer E Alkhalifa, Nour F Al-Ghraiybah, Julia Odum, John G Shunnarah, Nataleigh Austin, Amal Kaddoumi, Agueda A Rostagno, Jorge Ghiso · 2023

Read Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted Strategies by Amer E Alkhalifa, Nour F Al-Ghraiybah, Julia Odum, John G Shunnarah, Nataleigh Austin, Amal Kaddoumi, Agueda A Rostagno, Jorge Ghiso (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10671257.txt.

Description

A peer-reviewed research article from Europe PMC (2023). The blood–brain barrier (BBB) is a unique and selective feature of the central nervous system’s vasculature. BBB dysfunction has been observed as an early sign of Alzheimer’s Disease (AD) before the onset of dementia or neurodegeneration. The intricate relationship between the BBB and the pathogenesis of AD, especially in the context of neurovascular coupling and the overlap of pathophysiology in neurodegenerative and cerebrovascular diseases, underscores the urgency to understand the BBB’s role more deeply.

Catalog record

CREATORAmer E Alkhalifa, Nour F Al-Ghraiybah, Julia Odum, John G Shunnarah, Nataleigh Austin, Amal Kaddoumi, Agueda A Rostagno, Jorge Ghiso
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE83 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10671257

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