Crucial Role of Foxp3 Gene Expression and Mutation in Systemic Lupus Erythematosus, Inferred from Computational and Experimental Approaches

Zahra Birjan, Khalil Khashei Varnamkhasti, Sara Parhoudeh, Leila Naeimi, Sirous Naeimi · 2023

Read Crucial Role of Foxp3 Gene Expression and Mutation in Systemic Lupus Erythematosus, Inferred from Computational and Experimental Approaches by Zahra Birjan, Khalil Khashei Varnamkhasti, Sara Parhoudeh, Leila Naeimi, Sirous Naeimi (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10670696.txt.

Description

The impaired suppressive function of regulatory T cells is well-understood in systemic lupus erythematosus. This is likely due to changes in Foxp3 expression that are crucial for regulatory T-cell stability and function. There are a few reports on the correlation between the Foxp3 altered expression level and single-nucleotide polymorphisms within the Foxp3 locus.

Catalog record

CREATORZahra Birjan, Khalil Khashei Varnamkhasti, Sara Parhoudeh, Leila Naeimi, Sirous Naeimi
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10670696

Browse the full library · About the Tower of Babel