Impaired end joining induces cardiac atrophy in a Hutchinson–Gilford progeria mouse model
Yu Chen, Shiqi Huang, Zhen Cui, Xiaoxiang Sun, Yansong Tang, Hongjie Zhang, Zhixi Chen, Rui Jiang, Weina Zhang, Xue Li, Jiayu Chen, Baohua Liu, Ying Jiang, Ke Wei, Zhiyong Mao · 2023
Read Impaired end joining induces cardiac atrophy in a Hutchinson–Gilford progeria mouse model by Yu Chen, Shiqi Huang, Zhen Cui, Xiaoxiang Sun, Yansong Tang, Hongjie Zhang, Zhixi Chen, Rui Jiang, Weina Zhang, Xue Li, Jiayu Chen, Baohua Liu, Ying Jiang, Ke Wei, Zhiyong Mao (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10666128.txt.
Description
SignificanceCardiovascular compromise is the leading cause of death in patients with Hutchinson–Gilford progeria syndrome (HGPS). Although the mechanisms of vascular pathologies are documented, how heart dysfunctions develop in HGPS patients remains elusive. Here, we reported a phenotype of cardiac atrophy and a defect in DNA repair in HGPS mouse hearts.
Catalog record
| CREATOR | Yu Chen, Shiqi Huang, Zhen Cui, Xiaoxiang Sun, Yansong Tang, Hongjie Zhang, Zhixi Chen, Rui Jiang, Weina Zhang, Xue Li, Jiayu Chen, Baohua Liu, Ying Jiang, Ke Wei, Zhiyong Mao |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |