Leptin Induces MMP-1 Expression Through the RhoA/ERK1/2/NF-κB Axis in Human Intervertebral Disc Cartilage Endplate-Derived Stem Cells
Kuo-Feng Hua, Lan-Hui Li, Hsin-Chiao Yu, Wei-Ting Wong, Hsien-Ta Hsu · 2023
Read Leptin Induces MMP-1 Expression Through the RhoA/ERK1/2/NF-κB Axis in Human Intervertebral Disc Cartilage Endplate-Derived Stem Cells by Kuo-Feng Hua, Lan-Hui Li, Hsin-Chiao Yu, Wei-Ting Wong, Hsien-Ta Hsu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10657743.txt.
Description
PurposeIntervertebral disc (IVD) degeneration, associated with aging, may cause low back pain and disability, with obesity as a significant risk factor. In a prior study, we found a positive correlation between IVD degeneration and levels of matrix metalloproteinase-1 (MMP-1) and leptin. Yet, the interaction between MMP-1 and leptin in IVD degeneration is unclear.
Catalog record
| CREATOR | Kuo-Feng Hua, Lan-Hui Li, Hsin-Chiao Yu, Wei-Ting Wong, Hsien-Ta Hsu |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |