Clinical EEG slowing induced by electroconvulsive therapy is better described by increased frontal aperiodic activity
Sydney E Smith, Vincent Ma, Celene Gonzalez, Angela Chapman, David Printz, Bradley Voytek, Maryam Soltani · 2023
Read Clinical EEG slowing induced by electroconvulsive therapy is better described by increased frontal aperiodic activity by Sydney E Smith, Vincent Ma, Celene Gonzalez, Angela Chapman, David Printz, Bradley Voytek, Maryam Soltani (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10651871.txt.
Description
Sydney Smith and co-authors rethink what brain wave slowing after shock therapy for depression really means, in a 2023 study. The therapy is among the best for hard to treat depression, yet how it works in the brain is unclear. Its EEG trace slows, and that slowing was long read as more slow waves.
In nine patients, the team split the signal into true rhythms and a sloped background part. The background slope rose with treatment and explained the slowing better than slow wave power did, and it tracked how much patients improved. Models link a steeper slope to stronger inhibition, hinting the therapy restores a healthy balance in frontal areas.
Catalog record
| CREATOR | Sydney E Smith, Vincent Ma, Celene Gonzalez, Angela Chapman, David Printz, Bradley Voytek, Maryam Soltani |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |