ATP-responsive Mn(ii)-based T1 contrast agent for MRI†
Sellamuthu Anbu, Lawerence Kenning, Graeme J. Stasiuk · 2023
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Description
A novel diacetylpyridylcarbohydrazide–DAPyCOHz-based manganese(ii) chelate with dipicolylamine/zinc(ii) (DPA/Zn2+) arms (MnLDPA-Zn2) was developed for adenosine triphosphate (ATP) responsive magnetic resonance imaging (MRI) T1 contrast applications. Compound 2 shows enhanced relaxivity (r1 = 11.52 mM−1 s−1) upon selective ATP binding over other phosphates.
Catalog record
| CREATOR | Sellamuthu Anbu, Lawerence Kenning, Graeme J. Stasiuk |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |