Detecting continuous structural heterogeneity in single-molecule localization microscopy data
Sobhan Haghparast, Sjoerd Stallinga, Bernd Rieger · 2023
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Description
Fusion of multiple chemically identical complexes, so-called particles, in localization microscopy, can improve the signal-to-noise ratio and overcome under-labeling. To this end, structural homogeneity of the data must be assumed. Biological heterogeneity, however, could be present in the data originating from distinct conformational variations or (continuous) variations in particle shapes.
Catalog record
| CREATOR | Sobhan Haghparast, Sjoerd Stallinga, Bernd Rieger |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |