High throughput method for detecting murine brain atrophy using a clinical 3T MRI
Michael Linzey, Krista DiSano, Nora Welsh, James C. Ford, Francesca Gilli, Heather Wishart, Andrew Pachner · 2023
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Description
BackgroundThere is a lack of understanding of the mechanisms by which the CNS is injured in multiple sclerosis (MS). Since Theiler’s murine encephalomyelitis virus (TMEV) infection in SJL/J mice is an established model of progressive disability in MS, and CNS atrophy correlates with progressive disability in MS, we used in vivo MRI to quantify total ventricular volume in TMEV infection.
Catalog record
| CREATOR | Michael Linzey, Krista DiSano, Nora Welsh, James C. Ford, Francesca Gilli, Heather Wishart, Andrew Pachner |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |