Distinct NGS mutational landscape and prognostic implications in early-onset colorectal cancer: A dual-cohort analysis of TCGA PanCancer Atlas and MSK-IMPACT 50K
Elif Sertesen Çamöz, Osman Bilge Kaya, Hakan Erçelebi, Cengiz Karaçin, Yunus Kasım Terzi, Zerrin Yılmaz Çelik · 2026
Read Distinct NGS mutational landscape and prognostic implications in early-onset colorectal cancer: A dual-cohort analysis of TCGA PanCancer Atlas and MSK-IMPACT 50K by Elif Sertesen Çamöz, Osman Bilge Kaya, Hakan Erçelebi, Cengiz Karaçin, Yunus Kasım Terzi, Zerrin Yılmaz Çelik (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0359094.txt.
Description
Elif Sertesen Çamöz and five colleagues wrote this 2026 PLOS ONE research article on early-onset colorectal cancer, bowel cancer arising in younger adults. It describes a distinct NGS mutational landscape, the pattern of gene mutations read by next-generation sequencing, and its prognostic implications, what the pattern suggests about outcomes.
The analysis is dual-cohort, drawing on two large cancer datasets: the PanCancer Atlas of TCGA and the MSK-IMPACT 50K cohort. Early-onset cases are rising for reasons still debated, so showing their mutations differ from typical cases matters. Oncologists and cancer geneticists treating younger patients are the readers for a two-cohort mutation map.
Catalog record
| CREATOR | Elif Sertesen Çamöz, Osman Bilge Kaya, Hakan Erçelebi, Cengiz Karaçin, Yunus Kasım Terzi, Zerrin Yılmaz Çelik |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32297 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |