Apoptosis-related genes bridge inflammatory bowel disease and osteoporosis: A bioinformatic analysis
Yue Su, Xiaohui Luo, Haitao Xu · 2026
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Description
Yue Su and co-authors searched for cell-death genes that connect bowel inflammation with thinning bones. Inflammatory bowel disease often arrives with osteoporosis, and the shared machinery is unclear. Their 2026 analysis mined public gene datasets for both diseases, then layered network and regression methods to narrow the field.
Two genes survived every filter and tracked with the course of both conditions. One builds a signalling protein tied to bone growth; the other is an inflammation alarm protein. Enrichment checks placed the wider gene set in immune and bone-relevant pathways. Su and colleagues present the pair as candidate bridges between the diseases, to be tested in laboratory and clinical work before any treatment claims.
Catalog record
| CREATOR | Yue Su, Xiaohui Luo, Haitao Xu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27104 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |