Development of an asthma policy model for Canada: Lifetime Exposures and Asthma outcomes Projection
Tae Yoon Lee, John Petkau, Kate M Johnson, Stuart E Turvey, Amin Adibi, Padmaja Subbarao, Ainsleigh Hill, Mark Ewert · 2026
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Description
Tae Yoon Lee and colleagues built LEAP, a computer model that simulates asthma across entire Canadian lifetimes to help governments plan ahead. The model follows a shifting open population person by person through five linked parts. They cover births and deaths, risk factors, developing asthma, living with it, and the costs and quality of life that follow. Early versions focus on age, sex, family history, and antibiotic exposure in the first year of life.
Calibrated against national databases and a long-running birth cohort, the model reproduced real population projections and asthma rates closely. It is released openly as free software for other researchers to extend. The authors aim it at testing early-life interventions on paper, such as changing infant antibiotic use, before any province spends real money on them.
Catalog record
| CREATOR | Tae Yoon Lee, John Petkau, Kate M Johnson, Stuart E Turvey, Amin Adibi, Padmaja Subbarao, Ainsleigh Hill, Mark Ewert |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45822 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |