Plasma vitamin C levels are associated with brain structural networks on MRI: A large cohort study

Haruka Nagaya, Keita Watanabe, Tomohiro Shintaku, Miho Sasaki, Jusei Kudo, Sera Kasai, Yuka Ishimoto, Kana Saito · 2026

Read Plasma vitamin C levels are associated with brain structural networks on MRI: A large cohort study by Haruka Nagaya, Keita Watanabe, Tomohiro Shintaku, Miho Sasaki, Jusei Kudo, Sera Kasai, Yuka Ishimoto, Kana Saito (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0348504.txt.

Description

Haruka Nagaya and colleagues linked blood vitamin C levels with brain scans in just over two thousand older adults. Vitamin C in food has been tied to lower risk of thinking decline, yet direct links to brain structure were unclear. Scans measured grey and white matter volumes and the strength of a key resting brain network, with many health and habit factors counted.

Low vitamin C in blood went with a lower share of grey matter and weaker network links, even after age, schooling, illness, smoking, drinking, and activity were taken into account. A snapshot cannot prove that vitamin C protects the brain. Still, the tight link in a large group makes diet and brain ageing worth closer, longer study.

Catalog record

CREATORHaruka Nagaya, Keita Watanabe, Tomohiro Shintaku, Miho Sasaki, Jusei Kudo, Sera Kasai, Yuka Ishimoto, Kana Saito
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40894
LICENSECC_BY
RIGHTSCC BY
SOURCEPLOS

Source: https://doi.org/10.1371/journal.pone.0348504

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