Non-targeted metabolomics reveals myocardial metabolic alterations in epileptic rats
Yue Hu, Yusen Wang, Qinghong Mao, Shisheng Zhu, Li Zhang · 2026
Read Non-targeted metabolomics reveals myocardial metabolic alterations in epileptic rats by Yue Hu, Yusen Wang, Qinghong Mao, Shisheng Zhu, Li Zhang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0346628.txt.
Description
Yue Hu and colleagues took a full chemical scan of heart muscle from rats with epilepsy, hunting for shifts that might help explain sudden death in this disease. Such deaths are tied to the heart, but the chain of events is still not known. The scan reads hundreds of small molecules at once, and the team set the heart scans of sick rats next to those of healthy ones.
Clear gaps split the two sets of scans, and a short list of molecules stood out as changed the most. Those shifts point to the fuel and signal paths the sick heart seems to rewire. If the same marks show up in people, they could one day flag the patients at most risk, and the path map gives labs firm leads to test.
Catalog record
| CREATOR | Yue Hu, Yusen Wang, Qinghong Mao, Shisheng Zhu, Li Zhang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37804 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |