Postmastectomy radiotherapy in pN1 breast cancer: Survival outcomes and prognostic factors from a single-institution cohort

Raksha M Narasimhan, Aren Singh Saini, Kayla Samimi, Ifeanyichukwu Ogobuiro, Xuesen Zhao, Sunwoo Han, Cristiane Takita, Crystal S Taswell · 2026

Read Postmastectomy radiotherapy in pN1 breast cancer: Survival outcomes and prognostic factors from a single-institution cohort by Raksha M Narasimhan, Aren Singh Saini, Kayla Samimi, Ifeanyichukwu Ogobuiro, Xuesen Zhao, Sunwoo Han, Cristiane Takita, Crystal S Taswell (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0341754.txt.

Description

Raksha M Narasimhan, Crystal S Taswell, and co-authors looked back at women treated for early breast cancer that had spread to a few nearby lymph nodes. After mastectomy, doctors still debate whether radiation to the chest wall helps these patients live longer or stay cancer free. Their 2026 review covered women treated at one center over more than two decades.

Only fifty-seven patients fit the study, and about two in five received radiation. Radiation was not linked to better survival or fewer recurrences, even in the aggressive triple-negative type. Hormone therapy did help, while having more involved nodes predicted worse outcomes. The authors say treatment choices should rest on each patient's tumor traits and overall therapy, though the small group limits firm answers.

Catalog record

CREATORRaksha M Narasimhan, Aren Singh Saini, Kayla Samimi, Ifeanyichukwu Ogobuiro, Xuesen Zhao, Sunwoo Han, Cristiane Takita, Crystal S Taswell
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34165
LICENSECC_BY
RIGHTSCC BY
SOURCEPLOS

Source: https://doi.org/10.1371/journal.pone.0341754

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