Association of urate-lowering therapies with abdominal aortic aneurysm growth and clinical events in men: A population-based cohort study

Katja Bøhling Dybdahl, Mathilde Bernal, Marie Dahl, DANCAVAS trialists , Lasse M Obel, Jes Sanddal Lindholt, Joachim S Skovbo · 2026

Read Association of urate-lowering therapies with abdominal aortic aneurysm growth and clinical events in men: A population-based cohort study by Katja Bøhling Dybdahl, Mathilde Bernal, Marie Dahl, DANCAVAS trialists , Lasse M Obel, Jes Sanddal Lindholt, Joachim S Skovbo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0341242.txt.

Description

Katja Bøhling Dybdahl and colleagues, including the DANCAVAS trialists, published this 2026 Danish cohort study of gout drugs and aortic aneurysms. A swollen belly aorta can rupture fatally, and urate-lowering gout medicines had been suggested to slow its growth. The team followed nearly a thousand screened men for five years through national registries.

Only a small share used the medicines, and their aneurysms grew no slower than other men's. Surgery, rupture, and death rates also showed no benefit. Dybdahl concludes these drugs should not be expected to protect men with aneurysms, whatever their value for gout.

Catalog record

CREATORKatja Bøhling Dybdahl, Mathilde Bernal, Marie Dahl, DANCAVAS trialists , Lasse M Obel, Jes Sanddal Lindholt, Joachim S Skovbo
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33745
LICENSECC_BY
RIGHTSCC BY
SOURCEPLOS

Source: https://doi.org/10.1371/journal.pone.0341242

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