Feeding a low-protein diet exacerbates the susceptibility to Citrobacter rodentium and dextran sulfate sodium-induced intestinal injury in mice

Mehakpreet K Thind, Mary Flanagan, Sanne de Wit, Aida Glembocki, Jiali Pan, Celine Cuinat, Sharon Leung, Shamsun Nahar Shaima · 2026

Read Feeding a low-protein diet exacerbates the susceptibility to Citrobacter rodentium and dextran sulfate sodium-induced intestinal injury in mice by Mehakpreet K Thind, Mary Flanagan, Sanne de Wit, Aida Glembocki, Jiali Pan, Celine Cuinat, Sharon Leung, Shamsun Nahar Shaima (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0335322.txt.

Description

Mehakpreet Thind and eight colleagues published this research article in PLOS ONE in 2026. Working with mice, they test how a low-protein diet affects gut injury. Two challenges are involved: infection with Citrobacter rodentium, a mouse gut pathogen, and colitis induced by dextran sulfate sodium, a chemical that injures the bowel.

As the title states, feeding too little protein worsens the mice's susceptibility to both kinds of intestinal injury. Nutrition and gut defense are tightly linked, and this experiment shows the cost of protein shortage under attack. The work speaks to researchers studying malnutrition and bowel disease, where underfed patients often fare worst.

Catalog record

CREATORMehakpreet K Thind, Mary Flanagan, Sanne de Wit, Aida Glembocki, Jiali Pan, Celine Cuinat, Sharon Leung, Shamsun Nahar Shaima
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37021
LICENSECC_BY
RIGHTSCC BY
SOURCEPLOS

Source: https://doi.org/10.1371/journal.pone.0335322

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