Regional VRE surveillance using routine centralised, multicentre whole genome sequencing
Djamayl L H H Engelen, Jean-Luc Murk, Veronica A T C Weterings, Heike Schmitt, Bram M W Diederen, Andreas L E van Arkel, Jaco J Verweij, Wouter van den Bijllaardt · 2026
Read Regional VRE surveillance using routine centralised, multicentre whole genome sequencing by Djamayl L H H Engelen, Jean-Luc Murk, Veronica A T C Weterings, Heike Schmitt, Bram M W Diederen, Andreas L E van Arkel, Jaco J Verweij, Wouter van den Bijllaardt (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0334734.txt.
Description
Djamayl Engelen and co-authors tested whether routine gene sequencing could track drug-resistant gut bacteria across a whole region. The germ, a form of Enterococcus that resists the antibiotic vancomycin, spreads quietly in hospitals. Five Dutch hospitals sent their isolates to one lab for a year of shared surveillance, and the lab read each germ's full genetic code.
Sequencing grouped most isolates with at least one match, and patient movement records showed nearly all spread happened inside a single hospital, with a few jumps between hospitals. The shared system exposed one outbreak spanning centers and two local ones. The authors argue that pooled sequencing gives infection teams a clearer map of how resistance travels.
Catalog record
| CREATOR | Djamayl L H H Engelen, Jean-Luc Murk, Veronica A T C Weterings, Heike Schmitt, Bram M W Diederen, Andreas L E van Arkel, Jaco J Verweij, Wouter van den Bijllaardt |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26484 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |