Prior contact lens wear reduces susceptibility of the superficially-injured cornea to bacterial adhesion

Yujia Yang, Orneika Flandrin, Sara J Abboud, Eric Jedel, David J Evans, Suzanne M J Fleiszig · 2026

Read Prior contact lens wear reduces susceptibility of the superficially-injured cornea to bacterial adhesion by Yujia Yang, Orneika Flandrin, Sara J Abboud, Eric Jedel, David J Evans, Suzanne M J Fleiszig (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0332009.txt.

Description

Yujia Yang, David J Evans, and Suzanne M J Fleiszig led a mouse study with a surprise twist. Mice wore a contact lens on one eye for a few days. Lens wear stirs mild swelling on the eye's surface. Then both eyes got a light scratch and a dose of germs. The team asked if the worn eye would fare worse. It fared better.

Germs stuck to the lens-worn eyes about half as much. This held for a mild eyelid germ and a harsh eye germ alike. Immune cells had also moved into the worn eyes in force. The team reads the lens stir as a kind of drill. It primes the eye to fight off germs after small harm.

Catalog record

CREATORYujia Yang, Orneika Flandrin, Sara J Abboud, Eric Jedel, David J Evans, Suzanne M J Fleiszig
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE33389
LICENSECC_BY
RIGHTSCC BY
SOURCEPLOS

Source: https://doi.org/10.1371/journal.pone.0332009

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