Markers of kidney tubule dysfunction and injury and long-term risk of acute kidney injury following coronary artery bypass graft surgery
Lauren Shingler, Ashutosh Tamhane, Ching-Min Chu, Jennifer A Frey, Emily B Levitan, Suzanne E Judd, Alexander L Bullen, Edward D Siew · 2026
Read Markers of kidney tubule dysfunction and injury and long-term risk of acute kidney injury following coronary artery bypass graft surgery by Lauren Shingler, Ashutosh Tamhane, Ching-Min Chu, Jennifer A Frey, Emily B Levitan, Suzanne E Judd, Alexander L Bullen, Edward D Siew (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0331996.txt.
Description
Lauren Shingler, Edward D Siew, and co-authors asked whether urine tests taken years before heart bypass surgery could warn of later kidney injury. About one in five bypass patients develops sudden kidney damage after the operation. Their 2026 study used a large national cohort of older American adults and focused on those who later had bypass surgery.
Four urine markers of kidney tubule health had been measured about five years before surgery. Higher levels of one marker tied to tubule strain meant higher odds of kidney injury, while higher levels of two protective markers meant lower odds. A fourth marker showed no link. The results hint that quiet kidney weakness, visible years ahead, shapes risk after major surgery.
Catalog record
| CREATOR | Lauren Shingler, Ashutosh Tamhane, Ching-Min Chu, Jennifer A Frey, Emily B Levitan, Suzanne E Judd, Alexander L Bullen, Edward D Siew |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27744 |
| LICENSE | CC_BY |
| RIGHTS | CC BY |
| SOURCE | PLOS |