Cell Membrane Is Impaired, Accompanied by Enhanced Type III Secretion System Expression in Yersinia pestis Deficient in RovA Regulator
Fengkun Yang, Yuehua Ke, Yafang Tan et al. · 2010
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Description
Yang, Ke, Tan and co-authors examined what happens to the plague bacterium when a key regulator is removed. In gut-infecting Yersinia relatives, the RovA regulator controls invasin, a protein for entering host tissue. In Yersinia pestis, the plague agent, invasin is already inactive.
Their 2010 study found that without RovA the cell membrane is damaged, while the type III secretion system, a needle for injecting host cells, is turned up. One regulator thus balances surface safety against attack machinery. That balance may shape how plague bacteria survive in fleas and mammals.
Catalog record
| CREATOR | Fengkun Yang, Yuehua Ke, Yafang Tan et al. |
|---|---|
| YEAR | 2010 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012840