Increased Postprandial Nonesterified Fatty Acid Appearance and Oxidation in Type 2 Diabetes Is Not Fully Established in Offspring of Diabetic Subjects

François Normand-Lauzière, Frédérique Frisch, Sébastien M. Labbé et al. · 2010

Read Increased Postprandial Nonesterified Fatty Acid Appearance and Oxidation in Type 2 Diabetes Is Not Fully Established in Offspring of Diabetic Subjects by François Normand-Lauzière, Frédérique Frisch, Sébastien M. Labbé et al. (2010) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0010956.txt.

Description

François Normand-Lauzière, Frédérique Frisch, Sébastien Labbé and co-authors published this metabolism study in PLOS ONE in 2010. Fat in the blood after meals is suspected of damaging tissues and seeding type 2 diabetes. People whose parents both have diabetes showed abnormal fat handling when fat was infused, and the team asked whether the same fault appears after real eating.

They traced labeled fat through healthy offspring of two diabetic parents, healthy people without diabetic relatives, and patients with diabetes, during fasting, insulin infusion, and steady oral intake of a standard meal. In the offspring, the abnormal pattern seen with infusions was not fully established after food. Normand-Lauzière and colleagues map how an inherited diabetes risk develops step by step, before disease itself arrives.

Catalog record

CREATORFrançois Normand-Lauzière, Frédérique Frisch, Sébastien M. Labbé et al.
YEAR2010
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010956

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