Lactobacillus johnsonii N6.2 Mitigates the Development of Type 1 Diabetes in BB-DP Rats
Ricardo Valladares, Dhyana Sankar, Nan Li et al. · 2010
Read Lactobacillus johnsonii N6.2 Mitigates the Development of Type 1 Diabetes in BB-DP Rats by Ricardo Valladares, Dhyana Sankar, Nan Li et al. (2010) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0010507.txt.
Description
Ricardo Valladares and colleagues fed a gut bacterium to diabetes-prone rats and slowed the disease for PLOS ONE in 2010. Type 1 diabetes arises when immunity attacks insulin-making cells. The gut lining and its microbes shape that immunity daily. A leaky gut barrier and skewed immune activity may help trigger the disease. The team gave rats a Lactobacillus strain, N6.2, and watched diabetes develop.
Rats receiving the bacterium developed diabetes less or later. A single microbe strain easing an autoimmune disease is a notable result. It supports the idea that gut microbes can be therapy, not just passengers. More work must find how the effect works. Still, this study gives the probiotic approach a concrete success.
Catalog record
| CREATOR | Ricardo Valladares, Dhyana Sankar, Nan Li et al. |
|---|---|
| YEAR | 2010 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010507