Feasibility and Diagnostic Utility of Antigen-Specific Interferon-γ Responses for Rapid Immunodiagnosis of Tuberculosis Using Induced Sputum

Tamaryn J. Cashmore, Jonathan G. Peter, Richard N. van Zyl-Smit et al. · 2010

Read Feasibility and Diagnostic Utility of Antigen-Specific Interferon-γ Responses for Rapid Immunodiagnosis of Tuberculosis Using Induced Sputum by Tamaryn J. Cashmore, Jonathan G. Peter, Richard N. van Zyl-Smit et al. (2010) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/plos-pone-0010389.txt.

Description

Tamaryn Cashmore and colleagues tested a faster way to diagnose tuberculosis in PLOS ONE in 2010. TB is hard to confirm when a patient's sputum has few germs or none to spare. Standard culture takes weeks, delaying treatment. Blood tests that measure immune signals can detect TB, but need good samples. The team tried using induced sputum, coughed up with help, for a rapid immune test.

They checked both whether the approach was practical and whether it gave correct answers. A test that works on easier samples could speed care in busy clinics. It could also catch cases that smear tests miss. TB control depends on finding cases early, before spread. This study probes one shortcut toward that goal.

Catalog record

CREATORTamaryn J. Cashmore, Jonathan G. Peter, Richard N. van Zyl-Smit et al.
YEAR2010
COLLECTIONPAPERS
FORMATTXT
FILE SIZE25 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010389

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