Stem Cell-Like Properties of the Endometrial Side Population: Implication in Endometrial Regeneration

Hirotaka Masuda, Yumi Matsuzaki, Emi Hiratsu et al. · 2010

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Description

Hirotaka Masuda and co-workers described stem-like cells in the womb lining for PLOS ONE in 2010. The lining, called the endometrium, regrows itself every month during a woman's fertile years. Such regrowth hints that stem-like cells live there. Cells that stray and implant elsewhere cause endometriosis, a painful condition affecting about one in ten women of fertile age. The team isolated a special side group of lining cells.

That side group behaved like stem cells in tests. It could be the source of the lining's monthly renewal. If so, it may also seed the stray growths of endometriosis. Finding the source cells gives that disease a possible root cause to target. It also opens ideas for rebuilding damaged womb lining.

Catalog record

CREATORHirotaka Masuda, Yumi Matsuzaki, Emi Hiratsu et al.
YEAR2010
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010387

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