Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2

Viivi Majava, Eugenia Polverini, Alberto Mazzini et al. · 2010

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Description

The authors were Viivi Majava, Eugenia Polverini, Alberto Mazzini, and others. Their 2010 PLOS ONE study characterized a myelin protein from the peripheral nerves. Myelin is a tightly packed, layered membrane that insulates selected nerve fibers. It wraps axons in both the central and peripheral nervous systems. It also carries a specific set of proteins suited to that wrapping job.

The team made and purified the human protein P2 in the laboratory. They then described its structure and function in detail. Knowing P2's shape helps explain myelin stability and diseases where peripheral myelin breaks down.

Catalog record

CREATORViivi Majava, Eugenia Polverini, Alberto Mazzini et al.
YEAR2010
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010300

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