Panton–Valentine Leukocidin Enhances the Severity of Community-Associated Methicillin-Resistant Staphylococcus aureus Rabbit Osteomyelitis
Anne-Claude Crémieux, Oana Dumitrescu, Gerard Lina et al. · 2009
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Description
Anne-Claude Crémieux, Oana Dumitrescu, Gerard Lina, and colleagues studied a bacterial toxin in bone infection in 2009. Community-associated MRSA had spread widely in the United States by then. Severe infections, including bone infection called osteomyelitis, were rising even in healthy children.
The authors test Panton-Valentine leukocidin, a toxin made by some Staphylococcus aureus strains. They use a rabbit model of MRSA osteomyelitis. They report that the toxin makes the bone infection more severe. Their findings sharpen the ongoing debate about which bacterial factors drive the very worst community MRSA cases.
Catalog record
| CREATOR | Anne-Claude Crémieux, Oana Dumitrescu, Gerard Lina et al. |
|---|---|
| YEAR | 2009 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| LICENSE | Creative Commons Attribution License |
| RIGHTS | CC BY |
| SOURCE | PLOS ONE |
Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007204