Similarities and Differences in Genome-Wide Expression Data of Six Organisms

Sven Bergmann, Jan Ihmels, Naama Barkai · 2004

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Description

Sven Bergmann, Jan Ihmels, and Naama Barkai compared gene activity data across six species in PLOS Biology in 2004. Their set spans simple and complex life, from yeast to humans. They asked how alike the patterns of gene switching are when the same kinds of genes are tracked across species.

Some patterns held up well across all six, while others were unique to each species. The shared parts point to core rules of how cells run their genes. The unique parts show where evolution has tuned each species to its own life. Work like this guides a basic choice in research. It shows when a finding in yeast or flies may hold in humans, and when it may not.

Catalog record

CREATORSven Bergmann, Jan Ihmels, Naama Barkai
YEAR2004
COLLECTIONPAPERS
FORMATTXT
FILE SIZE48 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPLOS ONE

Source: https://journals.plos.org/plosone/article?id=10.1371/journal.pbio.0020009

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