Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection
Lewis H. Kuller, Russell P. Tracy, Waldo Horacio Belloso, Stéphane De Wit, Fraser Drummond, Henry Clifford Lane, Bruno Ledergerber, Jens Dilling Lundgren, Jacqueline Neuhaus, Daniel E. Nixon, Nicholas I. Paton, James D. Neaton · 2008
Read Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection by Lewis H. Kuller, Russell P. Tracy, Waldo Horacio Belloso, Stéphane De Wit, Fraser Drummond, Henry Clifford Lane, Bruno Ledergerber, Jens Dilling Lundgren, Jacqueline Neuhaus, Daniel E. Nixon, Nicholas I. Paton, James D. Neaton (2008) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/openalex-w2153136696.txt.
Description
Lewis Kuller, Russell Tracy, Waldo Belloso, and colleagues published this study in PLoS Medicine in 2008. Within the SMART trial of HIV treatment strategies, patients assigned to intermittent therapy died more often than those on continuous therapy. The team asked whether inflammation and clotting markers in blood help explain that gap.
Stored samples from trial members were tested for six markers tied to inflammation and blood clotting. A case-control study compared patients who died with matched survivors. Higher marker levels near study entry and before death were linked to higher odds of dying. A second study tracked how the two treatment strategies changed these markers over the first month after assignment.
Catalog record
| CREATOR | Lewis H. Kuller, Russell P. Tracy, Waldo Horacio Belloso, Stéphane De Wit, Fraser Drummond, Henry Clifford Lane, Bruno Ledergerber, Jens Dilling Lundgren, Jacqueline Neuhaus, Daniel E. Nixon, Nicholas I. Paton, James D. Neaton |
|---|---|
| YEAR | 2008 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 71 KB |
| LICENSE | CC0 1.0 Universal |
| RIGHTS | CC0 |
| SOURCE | OpenAlex / PLoS Medicine |