Functional Convergence of Neurons Generated in the Developing and Adult Hippocampus

Diego Andrés Laplagne, Maria Soledad Esposito, Verónica C. Piatti, Nicolás A. Morgenstern, Chunmei Zhao, Henriette van Praag, Fred H. Gage, Alejandro Fabián Schinder · 2006

Read Functional Convergence of Neurons Generated in the Developing and Adult Hippocampus by Diego Andrés Laplagne, Maria Soledad Esposito, Verónica C. Piatti, Nicolás A. Morgenstern, Chunmei Zhao, Henriette van Praag, Fred H. Gage, Alejandro Fabián Schinder (2006) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/openalex-w2018743597.txt.

Description

Diego Laplagne, Maria Soledad Esposito, Veronica Piatti and colleagues compared new brain cells made at different life stages. Their paper appeared in PLoS Biology in 2006. Part of the hippocampus makes new neurons throughout life. The team asked if adult-made neurons work like those made early in life.

They labelled neuron parent cells in young and adult animals. The labels used glowing proteins of different colours. They then recorded signals from neighbouring neurons of different ages. Adult-born neurons received much the same inputs as early-born ones. They could also fire signals when stimulated. Their firing behaviour matched closely too. The authors propose that both groups form one functional population. The finding matters for understanding adult brain growth.

Catalog record

CREATORDiego Andrés Laplagne, Maria Soledad Esposito, Verónica C. Piatti, Nicolás A. Morgenstern, Chunmei Zhao, Henriette van Praag, Fred H. Gage, Alejandro Fabián Schinder
YEAR2006
COLLECTIONPAPERS
FORMATTXT
FILE SIZE66 KB
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEOpenAlex / PLoS Biology

Source: https://doi.org/10.1371/journal.pbio.0040409

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