Mitochondrial biogenesis: An update.
Popov LD. · 2020
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Description
Popov updates the science of mitochondrial biogenesis, the process by which cells build new mitochondria. The review appeared in the Journal of Cellular and Molecular Medicine. Cells launch this renewal when energy demand rises or stress hits. New mitochondria grow out of existing ones. Recent work has uncovered many of the proteins and genes involved.
Popov focuses on how the main players work together inside the cell. One theme is keeping mitochondrial mass and function in balance. Another covers the signals that switch biogenesis on or off. A third weighs medical uses of this knowledge. Cancer research features, since some tumors lean heavily on new mitochondria. Drugs that raise or block a master regulator called PGC-1 alpha appear throughout. Readers get a current map of the field.
Catalog record
| CREATOR | Popov LD. |
|---|---|
| YEAR | 2020 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |